Enzymatic Debridement
The gold standard in enzymatic debridement. Santyl selectively removes necrotic tissue while preserving healthy granulation tissue for optimal wound healing.
Santyl is an FDA-approved enzymatic debriding ointment containing collagenase, an enzyme derived from Clostridium histolyticum bacteria. It works by breaking down collagen in necrotic tissue, allowing the body to remove dead tissue naturally.
Unlike sharp debridement, Santyl is selective—it only targets necrotic collagen while leaving healthy tissue intact. This makes it ideal for patients who cannot tolerate sharp debridement or for wounds with fragile granulation tissue.
Only removes dead tissue, preserves healthy granulation
Applied once daily under appropriate dressing
Reimbursed under Medicare Part B and most insurance plans
60+ Years of Clinical Use
Proven safety and efficacy
Collagenase breaks down collagen in necrotic tissue
Body naturally removes liquefied necrotic material
Preserved granulation tissue promotes faster healing
Removes yellow slough without sharp instruments
Gentle debridement for bedridden patients
Continuous debridement between visits
Maintains clean wound bed after initial debridement
Our wound care specialists can determine if enzymatic debridement is right for you
Schedule Assessment