FDA-Approved Growth Factor

Regranex (Becaplermin) PDGF Gel

The first and only FDA-approved topical growth factor for diabetic foot ulcers. Regranex stimulates wound healing by promoting cell proliferation and new tissue formation.

What Is Regranex (PDGF)?

Regranex (becaplermin) is a recombinant human platelet-derived growth factor (PDGF-BB) gel approved by the FDA specifically for lower extremity diabetic neuropathic ulcers that extend into subcutaneous tissue or beyond.

PDGF is one of the body's natural wound healing signals. It stimulates fibroblast proliferation, angiogenesis (new blood vessel formation), and granulation tissue development—all critical for wound closure.

FDA Approved

First topical growth factor approved for diabetic foot ulcers

Proven Efficacy

Clinical studies show 30-50% improvement in healing rates

Medicare Covered

Reimbursed under Medicare Part B for qualifying ulcers

Registered Nurse Pediatritian Doctor Changing Medical Dressing on Foot Injury Wound during Treatment of Young Caucasian Girl Patient

25+ Years of Use

Trusted since 1997

How Regranex Promotes Healing

Cell Proliferation

Stimulates fibroblast division and migration

Angiogenesis

Promotes new blood vessel formation

Granulation Tissue

Accelerates formation of healthy wound bed

Wound Contraction

Promotes wound edges to contract and close

Regranex Application Protocol

1

Clean Wound Bed

Debride and remove necrotic tissue, rinse with saline

2

Apply Thin Layer

Measured amount spread evenly over wound surface

3

Cover with Dressing

Moist saline gauze covered with secondary dressing

4

Daily Application

Applied once daily for up to 20 weeks or until healed

Is Regranex Right for Your Diabetic Foot Ulcer?

Our specialists will evaluate if you're a candidate for growth factor therapy

Schedule Evaluation